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EBOO Ozone Therapy Treatment (Apheresis)

Extracorporeal Blood Oxygenation, Ozonation and Filtration blood cleansing.
Watch the video : How I Finally Healed from Lyme Disease – I Tried Everything!

EBOO ozone therapy is the most advanced minimally invasive intravenous therapies available to detox your blood. While there are a number of devices that can ozonate your blood in a precise and safe way, this is the only device that can actually filter your blood while it is being ozonated… and that is its greatest benefit.

That is why we call the treatment EBOO /F, for filtration.

Explore the photos below to get an in-depth view of the most commonly used methods of introducing ozone into the blood of a patient.

A Brief Overview of Ozone in Medicine

Ozone has a wide range of therapeutic uses in the human body. We are only going to touch on a few.
When introduced to the blood, ozone has been reported to activate the immune system by stimulating the release of growth factors and other mediators, increases the oxygen carrying capacity of red blood cells and reduces ischemia in vascular disease by increasing the red blood cells pliability and flexibility.
Ozone also reverses the rouleaux formations we see in the blood of Long COVID patients, immediately improving red blood cell function

Methods of Introducing Ozone into the Blood

There are several different methods of administering ozone into the blood of a patient. Minor autohemotherapy, also known as single dose ozone therapy is one. MAH or major autohemotherapy, also known as hyperbaric ozone therapy, or “the 10 pass device” is another. These are a couple of the most common ozone therapy treatments.
In the last 5 years, EBOO /F re-emerged in the U.S. and is quickly becoming the gold standard of ozone therapy due to the quantity of ozone it delivers and its ability to filter toxic debris from the blood.

Single Dose Ozone Therapy / Minor Autohemotherapy

Minor Autohemotherapy involves the extraction of the patient’s blood into an IV bag. Ozone is then introduced into the bag and mixed with the blood.
The ozone infused blood is then dripped back into the patient. This method of administration is also know has Single Dose Ozone Therapy or SDOT.
When performing Minor Autohemotherapy a nurse uses a syringe to infuse ozone into an IV bag full of the patient’s blood.
The “Egg” where the patient’s blood is infused with ozone. Sitting below, out of site, is the hyperbaric ozone therapy device.

High Dose Ozone Therapy / Major Autohemotherapy

During Hyperbaric Ozone Therapy a specific amount of the patient’s blood is removed under pressure into a plastic “egg-shaped” container. While in the container the blood is infused with ozone. When this process is complete, the ozone infused blood is returned to the patient.
The hyperbaric ozone therapy device does this 10 times, hence the “10 pass device” nickname. This method of administration is also know as High Dose Ozone Therapy or HDOT. Recent studies have shown that HDOT stimulates the mitochondria in blood mononuclear cells.

Extracorporeal Blood Oxygenation, Ozonation and Filtration

The “newest” administration of ozone into the blood of a patient is EBOO /F, also known as Recirculatory Hemoperfusion (RHP), Apheresis and Ozone Dialysis.

In actuality, it isn’t really new as it has been used and perfected overseas for some 30+ years now. For unknown reasons, EBOO Ozone Therapy recently started to be used again here in the U.S. and is quickly gaining in popularity due to its effectiveness.

EBOO ozone therapy uses a pump to extract the patient’s blood from one arm. The blood then enters a dialysis chamber (dialyzer) from the bottom and flows upwards around tiny tubules in the chamber that filter out harmful debris and toxins.

One of the newest EBOO ozone therapy devices known as the “Stratos”. It is the only device that is made in the U.S. and in our opinion is far superior to any other EBOO treatment device currently on the market.

The blood flows against a countercurrent of ozone. Once the blood has been filtered, purified and infused with ozone, it is returned to the patient via an IV in their other arm.

Explore the photos below to get an in-depth view of the EBOO /F (apheresis) device.

What is EBOO /F Ozone Therapy (Apheresis)?

Invented in the 1980s, EBOO /F has been regularly performed for at least two decades with no published reports of adverse events.
In the last 13 years. major improvements have been made to the technology. The EBOO /F ozone therapy device we use today was developed by an intensive collaboration between multiple academic institutions and industry partners.

How the Filtration Works

EBOO /F is somewhat similar to dialysis, which filters out of your blood waste chemicals that healthy kidneys normally accomplish for you .
It is a process in which different constituents of the blood can be separated from one another and treated individually.
  • Red blood cell
  • White blood cells
  • Plasma
  • Platelets/Stem Cells
The EBOO /F is engineered to cleanse your blood of physical debris that your body is not capable of.

Various apheresis filters called dialyzers are engineered differently and from different materials in order to filter out specifically targeted elements. Historically, dialyzers were designed as a last resort to capture and remove excess lipids from patients at risk for cardiovascular failure, who did not respond to conventional therapy.

The body has two primary mechanisms for cleansing and detoxing your blood, your kidneys and liver. However they are not good at removing some specific toxic debris that make us very sick.

The EBOO /F is essential in that it is engineered to cleanse your blood of physical debris that neither the kidneys, nor liver, are capable of removing.

Why is the EBOO /F Filtration Important?

In cases of chronic infections, such as:

Other common blood toxins:,

  • Heavy metals
  • Residuals for medications
  • Environmental toxins – pesticides etc.
  • Chemotherapy
  • Industrial toxins
  • Excessive and/or abnormal blood clotting
  • Micro clots
  • Etc.
The toxic blood comes out of one arm, goes through the EBOO ozone therapy device, is filtered and ozonated, then the cleansed and ozonated blood goes into the other arm.
Debris being removed from the patient’s blood. This debris will be captured by the EBOO /F filter. The purified, debris-free blood is then re-infused back into the patient.
Even after the original pathogen has been killed, many patients still suffer debilitating symptoms that destroy their lives. Many Integrative physicians believe that this is due to residual “debris” left over from the infection. Endotoxins, cellular debris from dead pathogens, biofilm, micro clots, abnormal clotting (a characteristic of CV19 and LHC) and even debris from our own tissues damaged by the infection and the medications used to kill it. Our kidneys and liver are not designed to clear this debris, so it persists in our body as toxins that wreak havoc on us.

The EBOO /F filtration is designed to clear this debris. We can actually see the “gunk” being sucked out of these patients, and captured by the filter, allowing purified blood to be re-infused back into them.

Many patients report immediate relief from their symptoms… literally during their first treatment with EBOO /F.

Explore the photos below to get an in-depth view of the debris the EBOO /F ozone therapy treatment (apheresis) removes from the blood.

What Conditions can Benefit from EBOO /F Ozone Therapy?

EBOO /F is used to aid a variety of chronic diseases including:

  • Auto-immune Diseases
  • Diabetes
  • Long-Haul COVID
  • Lyme Disease
  • Herpes
  • Hepatitis
  • Brain fog
  • Chronic fatigue states
  • Chronic bladder conditions
  • Colitis
  • Crohn’s disease
  • Stroke
  • Hypertension
  • Eczema and Psoriasis
  • Lipid disorders
  • Cardiovascular disease
  • Peripheral Arterial Disease (PAD)
  • Coronary Disease
  • Severe Dyslipidemia
  • Madelung Disease
  • Necrotizing Fasciitis

EBOO /F Treatment and Long COVID

Depending on the severity of the typical COVID patient’s symptoms EBOO /F sessions will range from 1 – 10 treatments. Rarely will we need to go beyond 5 treatments.

Watch more stories of Long COVID patients here.

Often “gunk” will be observed emerging within the flow of venous blood. “Gunk” will typically stop appearing by the third EBOO /F treatment. However, an IV chelation with disodium EDTA 1-2 days prior to the next EBOO /F treatment often releases additional “gunk”.
Watch the video : I was the Long COVID walking dead

Explore the photos below to get an in-depth view of debris in the blood and the filter / dialyzer that removes it.

Lab Results – What the Dialyzer Removes from the Blood

Patient 1143 – Blood Pre-EBOO /F and Blood Post-EBOO /F Ozone Treatment

The photo on the left is of the patient’s blood prior to receiving the EBOO /F treatment. The center photo is of the used dialyzer. The photo on the right is of the patient’s blood immediately after the EBOO /F treatment.

Pre-EBOO /F

The 1st photo is an Advanced Stain at 100X. Structure observed is suggestive of biofilm, clots and extracellular traps.

The 2nd photo is of the patient’s used EBOO /F filter fibers. Giemsa Stain at 100X. Structures observed suggestive of biofilm, clot and extracellular traps adhered to EBOO /F filter fiber.

Post-EBOO /F

The 3rd photo is an Advanced Stain at 400X. Normal blood was observed. No structures suggestive of biofilm observed. Platelet clotting / micro-clotting not observed.
PATIENT 1143 : The patient’s blood before and after treatment with the EBOO /F device. The photo on the left is before the treatment. The center photo is of a fiber inside the patient’s used dialyzer. The photo on the right is the patient’s blood immediately after the treatment.

Patient 1144 – Blood Pre-EBOO /F and Blood Post-EBOO /F Ozone Treatment

The photo on the left is of the patient’s blood prior to receiving the EBOO /F treatment. The center photo is of the patient’s used EBOO /F dialyzer. The photo on the right is of the patient’s blood immediately after the EBOO /F treatment.

Pre-EBOO /F

The 1st photo is an Advanced Stain at 400X. Structures observed are suggestive of biofilm, clots and extracellular traps present. Yellow arrow indicated structure suggestive of bacteria.

The 2nd photo is of the patient’s used EBOO /F dialyzer. Giemsa Stain at 1000X. Structures suggestive of biofilm, clot and extracellular traps observed suspended between two EBOO /F filter filaments.

Post-EBOO /F

The 3rd photo is an Advanced Stain at 400X. Normal blood was observed. No structures suggestive of biofilm observed. Platelet clotting / micro-clotting not observed.
PATIENT 1144 : The patient’s blood before and after treatment with the EBOO /F device. The photo on the left is before the treatment. The center photo is of the filaments inside the patient’s used dialyzer. The photo on the right is the patient’s blood immediately after the treatment.

Lab Results – Heavy Metals Removed by Dialyzer

Patient 1167 – Blood Pre-EBOO /F and Blood Post-EBOO /F Ozone Treatment

Aluminum, arsenic, cadmium, lead and mercury were significantly reduced in the patient’s blood following treatment with the EBOO/F device.

Lab analysis of heavy metals present in patient’s blood Pre and Post EBOO /F treatment. Most, if not all, were reduced.

Patient 1168 – Blood Pre-EBOO /F and Blood Post-EBOO /F Ozone Treatment

Aluminum, arsenic, lead and mercury were significantly reduced in the patient’s blood following treatment with the EBOO/F device.
Lab analysis of heavy metals present in patient’s blood Pre and Post EBOO /F treatment. Most, if not all, were reduced.

Patient 1169 – Blood Pre-EBOO /F and Blood Post-EBOO /F Ozone Treatment

Aluminum, arsenic, cadmium, and lead were significantly reduced in the patient’s blood following treatment with the EBOO/F device.
Lab analysis of heavy metals present in patient’s blood Pre and Post EBOO /F treatment. Most, if not all, were reduced.
Watch the video : I was vaccine injured, these treatments brought me back

Ashley – I Was Vax Injured and These Treatments Brought Me Back

“My name is “Ashley”, I’m a registered nurse from Canada and I’m here to share my experience with COVID-19 and my vaccination.

Some of the symptoms from the vaccination are the same as when I had COVID, but much, much worse. It’s like COVID on steroids. Then I developed a whole new set of symptoms that I never had before. 

January of 2022 is when I finally recovered from my vaccine injury. 

2 years of my life…”

Lisa – If You have Long COVID & Feel Hopeless, Just Know, There’s Hope for Healing

“I’m Lisa. I’m here because I have Long Haul COVID. I had to stay home. I just kept thinking, okay, it’ll be soon. I’m going to be healed soon. But the symptoms started getting worse. After several months it just gets wearing on you. You’re there, but you’re not. You’re not there.

To be able to do things after work again. It just feels like I’m able to live again. I feel like I have life back in me.

Watch the video : If You have Long COVID & Feel Hopeless, Just Know, There’s Hope for Healing.
If you have Long COVID and you’re feeling like there’s no end to it, or that it’s just hopeless, just know, that it’s not. There’s hope for… for healing. Definitely be encouraged by people who have been through it and who have come out on the other side.”

Explore the photos below to get an in-depth view of the EBOO /F Ozone Therapy (apheresis) Treatment.

Extracorporeal Blood Oxygenation, Ozonation and Filtration FAQs

Q. Is the EBOO /F the same as plasmapheresis?

A. There are numerous forms of Apheresis depending on what exactly is being filtered out of the blood. Plasmapheresis is one of these forms. The Apheresis device we are using is specifically designed to filter out of the blood, debris left over from chronic infections, such as endotoxins, particles of killed bacteria, cellular debris from damaged tissues, etc.

A. The procedure takes approximately an hour. In that time between 4 – 5 liters of blood are filtered. The typical adult has on average 4.5-5.5 liters of blood.

A. Physical debris left over from chronic infections and systemic inflammation.
This includes:

  1. Endotoxins, which are fragments of pathogenic bacteria, fungus and mold infections that have been killed.
  2. Biofilm, which is a kind of sludge that many pathogenic microbes create to hide in… and where our immune cells can not penetrate.
  3. Debris from our own tissues that have been damaged from the infecting microbes and/or from powerful antimicrobial pharmaceutical drugs.
  4. Micro clots – microscopic blood clots that are resistant to the body’s own fibrinolytic processes.

    Our kidneys and liver, which are extremely efficient in cleaning our blood from chemical toxins, are not good at cleaning the physical debris listed above.

     
     

A. As mentioned, the human body is not good at filtering the blood to get rid of toxic debris from chronic infections (see answer above). But to leave these toxic materials in the blood can make a person quite sick, and unable to function. The body deals with this by storing these toxins in our tissues, and out of circulation. Tissues such as fat can store an enormous amount of toxic substances, including drugs and medications. Additionally, all of our tissues are constructed within a system of Extracellular Matrix which holds our cells together. This ExtraCellular Matrix is designed to store an enormous amount of toxins away from the blood. Chelation therapy is designed to “shake loose” these toxins out of the tissues and back into the blood, where they can be successfully filtered and removed from your body.

A. Typically, IV chelation with a substance called EDTA is used. A great “side-benefit” derived from using chelation therapy is detoxification from Heavy Metals.

A. Depends on what condition your body is dealing with. As a reference, our patients who are suffering from chronic Lyme symptoms even after a successful Lyme “kill”, generally need 4-6 sessions, once per week. Their results are best if they have a chelation IV early in the week and their EBOO /F treatment 2-3 days later.

A. In the USA, it is forbidden to say that a treatment is a “cure” for a condition if it has not been validated by the FDA. Thus we can not use the “cure” word no matter how effective the EBOO /F treatment is. What we can say is: that the clinical results of using EBOO /F as a treatment for certain ailments is very effective compared to all other conventional treatments.

A. Yes. The blood comes out of one arm and the filtered blood is returned via the other arm.

A. Yes.

A. No. However, it would be helpful if you have had a blood test for the presence of the enzyme G6PD.

A. No. However, it would be helpful if you have had a blood test for the presence of the enzyme G6PD.

A. Yes, EBOO /F removes LDL cholesterol and fat deposits from the circulatory system.

A. If you have any kind of abnormal blood issues or bleeding issues, clotting, etc, we need to know about them.

A. Almost anybody. The main challenge is with people who have very poor veins, that are difficult to get good IV access.

A. Yes, EBOO /F removes LDL cholesterol and fat deposits from the circulatory system.

Learn More About the Science of EBOO /F and Ozone Therapy

Everything on our website comes from from reputable publications, books and scientific journals, most of which are available on PubMed and other government websites. These include Meta-Analysis’, Randomized Controlled Trials, Clinical Trials, Systematic Reviews, Books and Documents. We encourage you to read the science, in order to separate fact from fiction, so that you can arrive at a full understanding of what is best for your body. We would be honored to be a part of that educational journey with you.

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  2. N Di Paolo, V Bocci, D P Salvo, G Palasciano, M Biagioli, S Meini, F Galli, I Ciari, F Maccari, F Cappelletti, M Di Paolo, E Gaggiotti. Extracorporeal blood oxygenation and ozonation (EBOO): a controlled trial in patients with peripheral artery disease. 2005 Oct;28(10):1039-50.
  3. Di Paolo N, Bocci V, Cappelletti F, Petrini G, Gaggiotti E. Necrotizing fasciitis successfully treated with extracorporeal blood oxygenation and ozonization (EBOO). 2002 Dec;25(12):1194-8.
  4. Wu J, Tan CS, Yu H, Wang Y, Tian Y, Shao W, Zhang Y, Zhang K, Shao H, Ni G, Shen J, Galoforo A, Wu Q, Ming D. Recovery of Four COVID-19 Patients via Ozonated Autohemotherapy. 2020 Nov 4:100060.
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  8. Bocci V, Zanardi I, Travagli V, Di Paolo N. Oxygenation-ozonation of blood during extracorporeal circulation: in vitro efficiency of a new gas exchange device. Artif Organs. 2007 Sep;31(9):743-8.
  9. Di Paolo N, Bocci V, Garosi G, Borrelli E, Bravi A, Bruci A, Aldinucci C, Capotondo L. Extracorporeal blood oxygenation and ozonation (EBOO) in man. preliminary report. Int J Artif Organs. 2000 Feb;23(2):131-41.
  10. Moreno-Fernández A, Macías-García L, Valverde-Moreno R, Ortiz T, Fernández-Rodríguez A, Moliní-Estrada A, De-Miguel M. Autohemotherapy with ozone as a possible effective treatment for Fibromyalgia. Acta Reumatol Port. 2019 Sep 29;44(3):244-249.